Nausea Control by Needling at Acupuncture Point Neiguan (PC6) During an Intraoral Impression-Taking Procedure

The objective of this study was to evaluate the effectiveness of acupuncture point PC6 (Neiguan) in controlling nausea during intraoral impression taking. This study was conducted in Piracicaba, São Paulo, Brazil. The sample consisted of 33 adult volunteers with nausea, who were randomly divided into control and study groups, and treated with nonpenetrating sham acupuncture and real acupuncture, respectively, at acupoint PC6. The two groups had two maxillary impressions taken, one prior to acupuncture and the other after acupuncture. The nausea assessment was made using the visual analog scale, Gagging Severity Index (GSI), and Gagging Prevention Index. Volunteers' expectation that nausea would be reduced through acupuncture was also assessed. For statistical analysis, we used the t test and the Spearman correlation (p < 0.05). When assessed by Gagging Severity Index/Gagging Prevention Index, nausea was reduced in the real acupuncture group (p < 0.01). In the visual analog scale assessment, similar reductions of nausea were noted in both groups (p > 0.05). No correlation existed between the expected and the actual reductions in nausea. Our results indicate that acupoint PC6 was effective for controlling nausea during the maxillary impression-taking procedure. Patients' expectation did not influence the results.     

白芥子不同配比穴位贴敷防治支气管哮喘的皮肤反应及疗效分析

目的:研究白芥子不同配比穴位贴敷防治支气管哮喘所出现的皮肤反应与疗效之间关系。方法:将所纳入的90例支气管哮喘患者随机分为A、B、C 3组,每组30例。贴敷药物中除白芥子外,余药相同。A组全部为生白芥子,B组生白芥子、炒白芥子各半,C组全部为炒白芥子。三伏天穴位贴敷,每伏贴敷一次,共3次。观察由不同配比白芥子而引起的皮肤反应以及各组疗效。结果:穴位贴敷后A、B、C3组皮肤反应积分依次降低,3组皮肤反应差异有统计学意义(P<0.05),A、B、C3组临床总有效率分别为93.33%、90.00%、73.33%,3组疗效组间比较无显著差异(p>0.05)。结论:穴位贴敷防治支气管哮喘是一种行之有效的方法,随生白芥子比例增加3组患者皮肤反应逐渐加重,但并非皮肤反应越强疗效越显著,适度的皮肤反应即可达到良好的疗效。     

扶正抗感膏方配合耳穴贴压法治疗反复呼吸道感染32例患儿临床观察

目的:探讨扶正抗感膏方配合耳穴贴压法治疗小儿反复呼吸道感染(RRTI)缓解期(肺脾气虚证)的临床疗效及对免疫功能及血清微量元素变化的影响。方法:将64例患儿随机分为治疗组和对照组各32例,治疗组采用口服扶正抗感膏方配合双侧耳穴贴压法治疗,对照组给予转移因子口服液口服,两组均以8周为一个疗程,疗程结束后均随访1年。比较分析两组总疗效,检测治疗前后IgG、IgM、IgA及血清锌、铁、铜水平的变化情况。结果:治疗组总有效率为93.3%,对照组为68.9%;两组比较具有统计学意义(P<0.05);与治疗前及对照组相比,治疗组IgG、IgA、血锌、血铁水平均升高,具有统计学意义(P<0.05和P<0.01)。结论:扶正抗感膏方配合耳穴贴压法对肺脾气虚型小儿RRTI临床疗效显著,其机制与该疗法有效调节免疫功能、纠正锌等微量元素失衡有关。     

Effect of auricular point pressing therapy on postoperative pain of fracture: A protocol for systematic review and meta-analysis

Background:In clinical practices, postoperative fracture patients are often treated with analgesics. As one of the alternative therapies for nondrug analgesia, auricular point pressing has advantages of simple operation, easy to use, no injury and adverse reactions, and great potential for development. In this study, the effect of auricular point pressing therapy on postoperative pain of fracture was objectively evaluated through the method of meta-analysis, so as to provide evidence for clinical applications.Methods:PubMed, Web of Science, Cochrane Library, EMBASE, Wan fang Database, Chinese Scientific Journal Database, China National Knowledge Infrastructure Database, and Chinese Biomedical Literature Database were systematically searched and randomized controlled trials on auricular point pressing in the treatment of postoperative pain after fracture were includes. After independent literature screening, data extraction and quality evaluation by 2 researchers, the original data was retrieved, merged, and analyzed. RevMan 5.3 software was adopted for meta-analysisResults:This study could provide high-quality evidence to evaluate the effect of auricular point pressing therapy on postoperative pain of fracture.Conclusion:This systematic review explored whether auricular point pressing therapy is effective on the intervention of postoperative pain after fracture.OSF Registration Number:DOI 10.17605/OSF.IO/AZ4JQ.     

The clinical efficacy of acupoint sticking combined with massage to treatment functional dyspepsia: A protocol of systematic review and meta-analysis

Background:The objective of this meta-analysis was to summarize and identify the available evidence from studies to estimate the clinical value of acupoint sticking combined with massage (ASM) in the treatment of functional dyspepsia (FD), and provide clinicians with evidence on which to base their clinical decision making.Methods:This review will include all studies comparing clinical efficacy of ASM in the treatment of FD. The search strategy will be performed in 10 databases. We will not establish any limitations to language and publication status, published from inception to the August 2020. Two reviewers will screen, select studies, extract data, and assess quality independently. Outcome is alleviation of global dyspeptic symptoms, alleviation of individual dyspeptic symptoms, quality-of-life improvement, and safety. The methodological quality including the risk of bias of the included studies will be evaluated. We will carry out statistical analysis using RevMan 5.3 software.Results:This study will summarize current evidence to assess the efficacy and safety of ASM in the treatment of FD.Conclusion:The findings of this study will provide helpful evidence for the clinician, and will promote further studies, as well as studying the value of ASM.Registration number:INPLASY2020110072 (DOI number: 10.37766/inplasy2020.11.0072).     

从腰夹脊穴论治中风后平衡功能障碍针刺思路探析

平衡功能障碍是中风后常见后遗症,增加了患者跌倒的风险及患者的病痛和负担,延缓了康复的进程,影响功能的恢复。针刺治疗是治疗中风后平衡功能障碍的重要方法,临床多以脏腑辨证和经络辨证为基础,多采用头皮针、体针、芒针等方法,虽取得一定疗效,但仍存在相应的局限性,缺乏现代学理论依据;本文从经络辨证和现代医学核心肌群理论出发,选取处于腰部核心肌群的夹脊穴,既可以通督脉、调摄膀胱经之背俞穴,入络脑室,从而达到整体治疗、调整阴阳的目的,又可以松解神经,进而缓解肌痉挛,降低肌张力,提高平衡功能。最后提出以针刺腰部夹脊穴治疗中风后平衡功能障碍,期待在临床治疗中取得更好的效果。     

经皮穴位电刺激辅助全麻对乳腺癌根治术中镇痛效应和血流动力学的影响

目的 观察经皮穴位电刺激（TEAS）辅助全麻下对乳腺癌根治术中镇痛效应和血流动力学的影响。方法 选取来自温州医科大学附属第一医院2019 年7 月～2020 年2 月全麻下行乳腺癌根治术患者80 例,按随机数字表法随机分成两组：TEAS 组和对照组,每组各40 例。TEAS 组在麻醉诱导前30 min 行TEAS（取穴为双侧合谷、内关、足三里、三阴交）,直至手术结束。对照组予相同位置贴电极片,不予电刺激处理。两组患者均采用常规诱导后置入喉罩全麻。记录两组术中各时间点的MAP、HR 和脑电双频谱值（BIS）、拔管时间、术中麻醉用药情况。结果 两组患者的一般情况和手术情况无差异。TEAS 组的拔管时间较对照组缩短,术中瑞芬太尼用量减少（P＜0.05）;TEAS 组在插管后即刻（T1）、插管后5 min（T2）、拔管后即刻（T6）、拔管后3 min（T7）的MAP 水平显著低于对照组（P＜0.05）,TEAS 组在插管后即刻（T1）、插管后5 min（T2）、拔管后即刻（T6）的HR 水平显著低于对照组（P＜0.05）;TEAS 组的T1 时刻BIS 值显著低于对照组（P＜0.05）。结论 经皮穴位电刺激辅助全麻可以增强乳腺癌根治术中镇痛效应,减轻术中应激反应。     

喘可治穴位注射对非急性发作期支气管哮喘患者IFN-γ、IL-4和IL-17的影响及表观遗传学机制

目的 探讨喘可治穴位注射对非急性发作期支气管哮喘患者的表观遗传学机制。方法 90例非急性发作期支气管哮喘患者随机分为观察组和对照组。对照组常规治疗,观察组加用喘可治足三里穴位注射。结果 经治疗后,观察组患者的ACT评分显著高于对照组,5-mC 和5-hmC水平显著低于对照组。观察组患者的IFN-γ水平显著高于对照组。结论 喘可治穴位注射能显著改善患者的哮喘控制症状和肺功能,推测可能与调控机体DNA甲基化和羟甲基化,调节免疫反应有关。     

An insulin-dependent hypoglycaemia induced by electroacupuncture at the Zhongwan (CV12) acupoint in diabetic rats

Summary Acupuncture at the Zhongwan acupoint has been widely used in traditional Chinese medicine to relieve symptoms of diabetes mellitus. Our study investigated the effect on plasma glucose of electroacupuncture applied at the Zhongwan acupoint in rat diabetic models. Plasma concentrations of insulin, glucagon and β-endorphin were also determined using radioimmunoassay. A decrease in plasma glucose was observed in rats after electroacupuncture (15 Hz, 10 mA) for 30 min at the Zhongwan acupoint. This was observed in normal rats and rat models with Type II (non-insulin-dependent) diabetes mellitus. No significant effect on plasma glucose was observed in rat models with Type I (insulin-dependent) diabetes mellitus; neither the streptozotocin (STZ)-induced diabetic rats nor the genetic (BB/W) rats. Further, the hypoglycaemic action of electroacupuncture stimulation disappeared in rats with insulin-resistance induced by an injection of human long-acting insulin repeated daily to cause the loss of tolbutamide-induced hypoglycaemia. An insulin-related action can thus be hypothesised. This hypothesis is supported by an increase in plasma insulin-like immunoreactivity after electroacupuncture stimulation in normal rats. Participation of glucagon was ruled out because there was no change in plasma glucagon-like immunoreactivity resulting from electroacupuncture stimulation. In addition to an increase in plasma β-endorphin-like immunoreactivity, the plasma glucose lowering action of electroacupuncture stimulation at Zhongwan acupoint was abolished by naloxone in a sufficient dose to block opioid receptors. Thus we suggest that electroacupuncture stimulation at the Zhongwan acupoint induces secretion of endogenous β-endorphin which reduces plasma glucose concentration in an insulin-dependent manner. [Diabetologia (1999) 42: 250–255] Received: 8 June 1998 and in final revised form: 5 October 1998